VelociHum is our immunodeficient mouse platform that can be used to accurately test human therapeutics against human immune cells and to study human tumor models.

VelociMouse dramatically shortens the timeframe needed to engineer genetically modified mouse models, while reducing cost and improving precision. Once a target is validated, a specific …

Feb 11, 2014 · This manuscript shows that this genomic engineering feat resulted in a unique kind of “HumAb” mouse. Dubbed VelocImmune, these mice efficiently generate antibodies that can …

Dec 15, 2009 · Here I describe the VelocImmune® mouse created several years ago by megabase-scale humanization of the variable portion of mouse immunoglobulin (Ig) loci, by far …

Apr 8, 2014 · We show that these mice, termed VelocImmune mice because they were generated using VelociGene technology, efficiently produce human:mouse hybrid antibodies (that are …

In contrast to HuMab mouse technologies, VelocImmune mice utilise the authentic murine loci and expression control regions for accurate regulation and antibody production, and through the …

Immunizations of VelocImmune mice generate robust humoral responses from which a large diversity of monoclonal antibodies can be isolated. Thus, VelocImmune mice are a unique …

VelocImmune mice, which are a part of the VelociGene platform, represent a new standard for generating human antibodies, as their precisely humanized immune systems appear to work …

VelociGene allows Regeneron to produce mouse embryonic stem (ES) cells rapidly for elucidating the function of the altered genes. VelociMouse allows Regeneron scientists to generate …

This manuscript shows that this genomic engineering feat resulted in a unique kind of "HumAb" mouse. Dubbed VelocImmune, these mice efficiently generate antibodies that can be rapidly …