Somatic cell nuclear transfer, technique in which the nucleus of a somatic (body) cell is transferred to the cytoplasm of an enucleated egg (an egg that has had its own nucleus removed). Once inside the egg, the somatic nucleus is reprogrammed by egg cytoplasmic factors to become a zygote (fertilized egg) nucleus.

Somatic cell nuclear transfer is a technique for cloning in which the nucleus of a somatic cell is transferred to the cytoplasm of an enucleated egg. After the somatic cell transfers, the cytoplasmic factors affect the nucleus to become a zygote.

Somatic cell cloning (cloning or nuclear transfer) is a technique in which the nucleus (DNA) of a somatic cell is transferred into an enucleated metaphase-II oocyte for the generation of a new individual, genetically identical to the somatic cell donor (Figure 1).

The donor nucleus used for nuclear transfer may come from an undifferentiated embryonic cell or from a differentiated adult cell (somatic cell); in the latter case, the technique is called somatic cell nuclear transfer (SCNT).

3 days ago · In addition to providing a means of rescuing and propagating valuable genetics, somatic cell nuclear transfer (SCNT) research has contributed knowledge that has led to the direct reprogramming of cells (e.g., to induce pluripotent stem cells) and a better understanding of epigenetic regulation during embryonic development.

Somatic Cell Nuclear Transfer (SCNT) is the process by which the nucleus of an oocyte (egg cell) is removed and is replaced with the nucleus of a somatic (body) cell (examples include skin, heart, or nerve cell). The two entities fuse to become one and factors in the oocyte cause the somatic nucleus to reprogram to a pluripotent state.

Somatic Cell Nuclear Transfer (SCNT) is performed by transferring a nucleus isolated from a somatic cell (or the intact somatic cell) into an enucleated zygote. This technology was developed and used to produce both homoplasmic and heteroplasmic cybrid models.

Somatic cell nuclear transfer (SCNT) is the process of transplanting nuclei from adult cells into oocytes or blastocysts and allowing them to grow and differentiate, producing pluripotent cells. Figure 1 illustrates SCNT. This process has both reproductive and therapeutic implications.

Somatic cell nuclear transfer is used primarily for generating cells and tissues that are immunocompatible with the somatic cell donor, a concept known as therapeutic cloning. Originally suggested in 1999, the production of patient-specific or genetically identical embryonic stem cells (ESCs) for research and therapeutic purposes emphasizes the ...

Mar 12, 2020 · Somatic cell nuclear transfer is a classical technique in biotechnology for reprogramming the nucleus of a somatic cell (Singh et al. 2019). The cell can resume pluripotency and further differentiate from the embryonic state into specific tissues and cell types that inherited the original genotype in the donor nucleus.