This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Extracellular vesicles (EVs) are small vesicles released by cells into the surrounding environment, carrying biomolecules such as proteins, miRNA, etc., involved in intercellular communication and ...

Get Instant Summarized Text (Gist) Extracellular vesicles (EVs) from cancer cells play a crucial role in tumor spread by facilitating intercellular communication. Recent imaging studies reveal ...

State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectro-Chemical Analysis & Instrumentation, Department ...

Small extracellular vesicles (sEVs) released by endometrial epithelial cells during the secretory phase have been shown to facilitate trophoblast invasion; however, the molecular mechanisms that ...

The final step of exocytosis in yeast involves the assembly of two t-SNAREs, Sso1/2 and Sec9, with the v-SNARE, Snc1/2, on secretory vesicles. The rate-limiting step in this process is the formation ...

Protein pore-mediated transport of solutes across vesicle boundaries. (a) Schematic diagram. (b) Experimental results showing that a GUV initially excluding FITC dye increases in fluorescence relative ...