New method for designing artificial proteins Date: November 21, 2024 Source: Technical University of Munich (TUM) Summary: Protein design aims to create customized antibodies for therapies ...

Researchers developed an AI-powered protein design method using Alphafold2 and gradient descent optimization. The approach allows precise tailoring of large proteins with desired properties, such as ...

Functional protein design, particularly for proteins binding to small molecules such as enzymes and biosensors, is crucial for drug discovery and biomedical applications. Traditional methods based ...

View Full Profile. Learn about our Editorial Policies. Rational design is the classical protein engineering method that involves site directed mutagenesis. 7 Scientists perform specific point ...

The latest advance in the competitive and fast-moving field came Thursday when Generate disclosed details about its new method for protein design in a paper posted on its website. It offers a rare ...

has created a method to design disordered proteins with specific biologically relevant properties. This advance teaches us more about the intricacies of protein folding and could allow us to build ...

Using the helical bundle protein as a framework, the team used state-of-the-art artificial intelligence methods to design sequences of amino acids that underlie the protein structures with the ...

Protein design is being guided by artificial intelligence ... kinds of properties have led to failures with more conventional methods.” Ranganathan sums up his case as follows: “Basically ...