NRF2 upregulates enzymes involved in GSH synthesis (e.g., GCLC, GCLM), GPX4, and heme oxygenase-1 (HO-1) while simultaneously enhancing iron storage (via ferritin) and export (via ferroportin) (42).

Credit: MPE “If you look at the distribution of the galaxy clusters in the sky in a spherical shell with a distance of 416 to 826 million light-years, you immediately notice a huge structure that ...

Background: Endothelial dysfunction is commonly accompanied by a reduced capacity for nitric oxide (NO) production and decreased NO sensitivity, playing a central role in numerous vascular diseases.

CMD-GEN is a structure-based framework for selective inhibitor design, combining coarsegrained pharmacophore sampling with generative models to optimize molecular stability, druglikeness ...

Investopedia / Yurle Villegas An organizational chart, or org chart, graphically represents an organization's structure by detailing the roles, responsibilities, and relationships between ...

She has 15+ years of experience as a financial writer and technical analyst. A firm's capital structure is a mix of borrowed money and investor funding that it uses to fund itself. When Meta ...