Life is thought to have begun when RNA began replicating itself, and researchers have got close to achieving this in the lab ...

A large-scale study (exRNAQC) outlines how blood tube type, RNA purification method, and processing time influence exRNA profiles. Results support new guidelines for researchers and diagnostic product ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

The process of mRNA encapsulation and LNP purification ... further complicating the challenge of this critical last step. mRNA is mixed with various inactive ingredients to create a stable and ...

The process is painstaking but also ... “This study evaluating an mRNA cancer immunotherapy is an important first step in hopefully developing a new treatment for patients with advanced cancers ...

But, as scientists look to model every aspect of mRNA processing, publicly available ... the TFF membrane using two consecutive wash steps. “This approach also enables the purification of ...

The process begins with the generation of ... With this innovative recipe for LNPs, Penn Engineers have taken a major step forward in advancing mRNA technology, offering hope for a faster and ...

Comparison of the kinetic rate constants for these steps across genes will provide novel insights ... These findings provide a foundation for future research into the mechanisms of mRNA processing and ...

In a process called deadenylation, the target mRNA is recruited by RNA-binding proteins ... scientists were able to take their work even one step further and demonstrate the potential of their ...

This article explains HPV mRNA E6/E7, what it means if a test detects it, and the next steps a person can take ... HPV mRNA E6/E7 refers to a process of certain high-risk types of HPV, in which ...

In our position [in] mRNA, we have several years of trial runs on the manufacturing technology platform, performing research-grade processing before we flipped over into GMP,” he said in the BIO ...