In effort to slow the opioid crisis, federal regulators plan to restrict a kratom compound available in smoke shops over the counter in Spokane and across the country. The Food and Drug Administration announced Tuesday their intention to designate 7-hydroxymitragynine as a controlled substance.

Data: Legislative Analysis and Public Policy Association; Note: Louisiana's kratom ban goes into effect Aug. 1, 2025; Map: Axios Visuals The FDA is cracking down on a potent compound found in kratom supplements: 7-hydroxymitragynine,