Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Researchers at the Max Planck Institute for Evolutionary Anthropology have addressed a longstanding challenge in CRISPR ...

multiple factors and elements were shown to coordinate transcription and translation, suggesting an intricate level of synchronization. This review discusses the molecular mechanisms that impact both ...

Researchers from Northwestern University have stumbled upon a previously unobserved function of a protein found in the cell nuclei of all flora and fauna. In addition to exporting materials out of the ...

The mechanism differs in eukaryotes and prokaryotes. Eukaryotes genes are regulated by transcription factors (a type of protein) which bind to a region known as the promoter region found just before ...

By binding to the promoter site on a DNA strand, RNAP along with transcription factors form a transcription pre-initiation complex (PIC). This initiates the process of transcription. The promoter ...

All major biological processes start after protein molecules known as transcription factors detect specific regulatory sequences on DNA and initiate genetic expression by associating to them. But in ...

A subset of eukaryotic transcription factors (TFs) possess the ability to reprogram one cell type into another. Genes important for cellular reprograming are typically located in closed chromatin, ...

Qatar Higher eukaryotic development is a complex and tightly regulated process, whereby transcription factors (TFs) play a key role in controlling the gene regulatory networks. Dysregulation of these ...

The course focuses on current understanding of the structure and function of eukaryotic transcription factors. Topics covered are: promoters, RNA polymerase II, general transcription factors and ...

In eukaryotes, basal transcription factors are required for RNA to perform its role at a transcription site. Basal transcription factors are considered the most basic group of proteins required ...