Detroit loss continues a trend — lack of takeaways has torpedoed the 49ers’ season 49ers can’t get the ball away from Lions, while Brock Purdy throws two interceptions in 40-34 loss ...

Detroit will take over at the 49ers' 43-yard line with 3:58 to go in the third quarter. 49ers 28, Lions 24: Jake Bates nails 57-yard FG. San Francisco edge rusher Nick Bosa got his second sack of ...

FINAL: Lions 40, 49ers 34. First downs: DET 23 SF 29 Total yards: DET 439 SF 475 Third downs: DET 9-14 SF 5-8 Red zone: DET 3-4 SF 5-5 Punts: ZERO. Jared Goff 26/34 303 yards 3 TDs ...

The 49ers outgained Detroit 260-211 and had a defensive stop on fourth down. 1:13, 2Q: Lions fail on 4th down in red zone, trail 21-13. The 49ers came up with the first defensive stop of the game.

San Francisco 49ers quarterback Brock Purdy began his career as the fourth quarterback on the depth chart, but his teammates wanted to see him play.

The San Francisco 49ers had a rough offseason after a down year in 2024, but there are plenty of reasons to believe they'll ...

The NFL season is still nearly two months away, but a handful of bets for Week 1 are already gaining traction among fans.

The Detroit Lions’ loss to the San Francisco 49ers on Jan. 28, some 11 months ago, remains a sore subject for those on this year’s team. They watched a 24-7 lead evaporate .

A 9-time Pro Bowler details how his unexpected release and quick return defined a dramatic offseason with the 49ers.

A top NFL ESPN analyst has handed out a surprisingly low ranking to San Francisco 49ers star RB Christian McCaffrey.

San Francisco 49ers cornerback Deommodore Lenoir was arrested Thursday in Los Angeles for resisting a peace officer, ...

LOS ANGELES (AP) — San Francisco 49ers player Deommodore Lenoir was arrested in Los Angeles on a charge of obstructing law ...