An ICMR-funded trial led by CMC Vellore demonstrated that CAR-T therapy, which uses a patient's own T cells to fight cancer, ...

neuromuscular blocking agents and foreign proteins (chimeric antibodies). In non-IgE-mediated drug allergy, different mechanisms are involved. These include cytotoxic/cytolytic reactions involving ...

next-generation immunomodulators and targeted therapies such as antibody-drug conjugates (ADCs) and innovative chimeric antigen receptor (CAR) T cell therapies. Based on its deep expertise in mRNA ...

Researchers from the Centenary Institute, in collaboration with the University of Sydney, have developed a powerful new tool ...

The past decade in oncology has been marked by the rise of immunotherapy, which leverages the immune system to attack tumors. For many solid tumors, immune checkpoint inhibitors have supplanted ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...

Nabla Bio's latest AI model update generates de novo antibodies for GPCRs with therapeutic-grade properties within a few ...

How do antibody engineers select isotypes? IgG1 has been the most popular choice by far and was used for 13 approved chimeric, humanized or fully human antibodies (compared with only two instances ...

We treated 428 patients who had active rheumatoid arthritis despite methotrexate therapy with placebo or infliximab, a chimeric monoclonal antibody against TNF-α, in intravenous doses of 3 or 10 ...

A decades-long scientific challenge in HIV vaccine development has been finding a way to train the immune system to produce antibodies that can target many variants of the virus. Traditional ...