Machine learning models have seeped into the fabric of our lives, from curating playlists to explaining hard concepts in a ...

Protein–protein interactions often play a crucial role in stabilizing protein–DNA complexes and thus facilitate site-specific DNA recognition. We have worked to incorporate such protein ...

Immunologists from the Babraham Institute have been the first to uncover a role for a family of RNA-binding proteins in the ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

Researchers have engineered a compact, high-specificity IscB variant, NovaIscB, for safe, persistent in vivo epigenome ...

The molecular pathways involved in antiviral defenses and counter-defenses in host-pathogen systems remain unclear. Researchers have used Neurospora crassa as a model organism to explore how RNA ...

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

Mechanistic studies revealed that SH6 degrades SALL4 protein through the CUL4A/CRBN pathway ... Next, we crystalized the structure of a different region of SALL4 called zinc finger cluster four (ZFC4) ...