C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

The FDA recently granted EXG-34217 Rare Pediatric Disease Designation (RPDD) and Regenerative Medicine Advanced Therapy (RMAT) Designation.

After testing the targeting capabilities of several different DNA binding domains, the team settled on a zinc finger protein—a little curlicue-shaped protein that performed the best in terms of ...

Gene Editing Tool Market AnalysisThe global gene editing tool market is on the cusp of a revolutionary expansion, projected to grow at an impressive CAGR of 18.4% from 2024 to 2034. Valued at USD 688.

Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired DNA sequence, and a DNA-cutting part of a restriction enzyme.

Sp1 is a protein that has multiple zinc-finger motifs, or regions known to bind to zinc; however, the inclusion of EDTA, an agent that chelates metal ions, inhibits zinc binding. Thus, notice that ...

The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in t(8; 16)(p11; p13) and inv(8)(p11q13) associated with acute myeloid leukemia. The other fusion partners involved are CBP and ...

Elixirgen Therapeutics, Inc. is a clinical-stage biotechnology company focused on the treatment of rare diseases and aging-associated diseases using its ZSCAN4 technology and mRNA platform ...

Co. Ltd. has described histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) inhibitors reported to be useful for ...

Researchers from the School of Metallurgy and Environment at Central South University, together with their collaborators, have proposed a novel buried interface strategy for stabilizing zinc anodes.