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Scientists produce human DNase1 in yeast for the first time, opening doors to wider clinical use and easier manufacturing.

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, ...

with the identification of cis-acting DNA elements in the promoters of eukaryotic cells that are required for transcriptional activation. Many promoters from both yeast and mammalian cells share ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

Researchers at Texas A&M found that metabolic molecules acetyl-CoA and SAM affect gene expression in yeast by altering ...

The human skin hosts a multitude of microorganisms, including fungi that could play a key role in our health. A recent study ...

Sterols are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic pathways. Researchers have used a novel approach to show how they ...

Donald Danforth Plant Science Center, St. Louis, Missouri 63132, Departments of Medicine and Cell Biology & Physiology, Washington University School of Medicine, St. Louis, Missouri 63110, and ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...

Ribosome attachment and scanning are impeded by structures in the 5′ UTR that can be resolved by RNA helicases Ded1 and eukaryotic translation initiation factor 4A (eIF4A), with cofactors eIF4B and ...