The recent completion of the final chromosome, synXVI, marks the end of the synthesis stage of the project ... Another direction is refining the yeast 2.0 organism. For example, breaking the ...

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Chromosome rearrangements within species are thought to contribute to reproductive isolation between species. This has now been shown directly by unrearranging yeast chromosomes to break down a ...

In an ambitious effort, researchers created a completely synthetic chromosome for yeast, a common organism found in baking and brewing. The real surprise? After carefully fixing some flaws ...

This has allowed us to develop a biotechnological method to produce taxol in yeast cells," says Sotirios Kampranis, Professor at the Department of Plant and Environmental Sciences and senior author of ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...

Yet producing the drug is complex, costly, and environmentally burdensome, as it currently relies on a complicated chemical semi-synthesis ... to produce taxol in yeast cells," says Sotirios ...

Here, we report the synthesis of a functional 272,871-base pair designer eukaryotic chromosome, synIII, which is based on the 316,617-base pair native Saccharomyces cerevisiae chromosome III. Changes ...