The recent completion of the final chromosome, synXVI, marks the end of the synthesis stage of the project ... Another direction is refining the yeast 2.0 organism. For example, breaking the ...

The protein DNase1 is one of the oldest biological agents in history. It has been on the market since 1958 and is now used, ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

This valuable study investigates how stochastic and deterministic factors are integrated during cellular decision-making, particularly in situations where cells differentiate into distinct fates ...

You have full access to this article via your institution. Figure 1: Domain organization of classical HDACs from yeast and humans. Table 1 Class I HDAC complexes and their composition in different ...

Here, we report the synthesis of a functional 272,871-base pair designer eukaryotic chromosome, synIII, which is based on the 316,617-base pair native Saccharomyces cerevisiae chromosome III. Changes ...

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