Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

While human naive PSCs can differentiate into both ... of naive-type induced pluripotent stem cells from chimpanzee somatic cells. Not only did they reveal key insights into the mechanisms ...

This week a group of researchers, bioethicists, publishers and theologians are discussing the merits of human heritable genome editing.

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint ...

A research team has developed and safely delivered a personalized gene editing therapy to treat an infant with a life-threatening, incurable genetic disease. The infant, who was diagnosed with the ...

Colossal uses gene editing to bring dire wolves back from extinction, marking a breakthrough in de-extinction science with the birth of Romulus and Remus.

While the medical world is melting down from the absolute apocalypse that is RFK Jr., it's good to celebrate that (at least ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

The case is detailed today in a study published by The New England Journal of Medicine and was presented at the American ...