Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help ...

FBLG READ THE FULL FBLG RESEARCH REPORT Business Update Preclinical Psoriasis Data Presented at SID Annual Meeting On May 16, 2025, FibroBiologics, Inc. (NASDAQ:FBLG) announced a poster presentation ...

As the authors reported in Radiology Case Reports, the patient had no history of cancer and had no pain, weakness, numbness, or other spine-related symptoms. Lab tests confirmed she had severe anemia; ...

Shanghai Ark Biopharmaceutical Co., Ltd. ("ArkBio") today announced positive top-line Phase II study results for its novel ...

A shift to ERBB growth factor mediated proliferation away from estrogen signaling is observed in resistant cancer cells in most tumors during treatment, partially facilitated by ERBB receptor ...

Histopathologically, PF features chronic inflammation, fibroblast proliferation, and excessive extracellular matrix deposition, predominantly collagen. Unlike inflammatory ILDs, IPF follows an ...

Researchers from Nanjing Medical University presented data from a study that aimed to investigate the role of amphiregulin (AREG) in activating intestinal fibroblasts and driving fibrogenesis. AREG ...

For a wound to heal properly, it must move from the inflammatory phase to the proliferation phase. During this phase, myofibroblasts, a specialized fibroblast, make the wound’s extracellular ...

Both in vitro and in vivo studies indicate that Ambra1 + Myo-sEV I/R, which carries mitochondrial components and mtDNA, can be internalized to promote pathological proliferation of fibroblasts ...

However, the mechanisms that control the timing and extent of cardiac fibroblast proliferation and ECM production are not known, hampering the development of antifibrotic strategies to prevent heart ...