The VDL is currently restructuring and not providing services at this time. For all request of viral vectors, please visit the Gene Vector Core Website or send an email to [email protected]. Since ...

Gene therapy, a technique that is revolutionizing the treatment of multiple genetic conditions, including eye and muscle diseases and blood disorders, requires efficient and specific delivery of the ...

An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

Engineering the replication of target DNA through cloning, or changing its genetic code through mutations, are detail-oriented processes whose foibles can spell disaster. Caitlin Smith looks at ...

Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...

Figure 1: Retroviral backbone of pSHAG-MAGIC2. To generate the hairpin primer, select a 'sense' sequence(s) of 22 nucleotides (nt) in length from the coding sequence of the gene of interest for ...

Genetic engineering, also known as genetic modification, is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to ...

Transgenic animals continue to play an essential role in many aspects of zebrafish research, including the development of disease models. The most widely used system for zebrafish transgenesis is the ...

GBU's reagent collection contains a library of open reading frames (ORFeome collaboration) consisting of about 18 600 fully verified cDNA clones, and a collection of full-length cDNAs (MGC collection) ...