This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...
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Testosterone helps release growth hormones, which stimulate tissue growth, and it connects with nuclear receptors in DNA, which causes protein synthesis (or muscle growth). Turner points out that ...
Androgens exert their effects largely by binding to nuclear androgen receptors to regulate gene expression, but they can also bind to receptors in plasma membranes to rapidly induce cellular ...
In a surprising discovery, scientists have found that the heart possesses 'sweet taste' receptors, similar to those on our tongues, and that stimulating these receptors with sweet substances can ...
Additionally, their research may explain why high consumption of artificially sweetened beverages is linked to arrhythmogenesis, or an irregular heartbeat. Not only are these sweet taste receptors ...
Although flies are a long leap from humans, many other mechanisms are conserved between the two species, so it’s possible that a similar metabolite sensor or stretch receptors in the stomach could be ...
Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...
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