Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

From antibody-drug conjugates to PARP inhibitors, innovative treatments are offering new hope for patients with ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

In this valuable study, the authors used rats to determine the receptor for a food-related perception that ... indicated that GPRC6A was expressed in a subset of type II taste cells in rat fungiform ...

There's something else to keep in mind when looking for the best family cell phone plans: unlimited data is the way to go more often than not. That way, you don't have to worry about running out ...

MB-105, a CD5-targeted CAR-T cell therapy, is being evaluated in a phase 2 trial for relapsed or refractory CD5-positive T-cell lymphoma. The trial, led by Dr. Swaminathan P. Iyer, will assess ...

The engineered high-affinity TCR with amino acid substitutions lead to T-cell activation and cancer cell death. lete-cel, letetresgene autoleucel; MHC, major histocompatibility complex; TCR, T-cell ...

Realising the potentially substantial benefits of chimeric antigen receptor (CAR) T-cell therapy for children with cancer is ... potentially out of their home country or in a different linguistic ...

The manufacturing of T cells in a tailor-made setting ... were used to profile the effector receptors. Anti CD107a (H4A3) antibody was used as measurement of degranulation functions. Anti Vβ3 (CH92) ...

Over the past few years, researchers have been looking at ways to use T cells to fight certain diseases such as cancer. This has led to the development of chimeric antigen receptor (CAR ...