Additionally, cells of the kidney express ACE-2 making them a potential target of the SARS-CoV-2 virus. Both uncontrolled viral replication and T-cell receptor (TCR ... which is facilitated by its ...

In this valuable study, the authors used rats to determine the receptor for a food-related perception that ... indicated that GPRC6A was expressed in a subset of type II taste cells in rat fungiform ...

Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer ...

Considered to be one of the greatest revolutions in cancer treatment, immunotherapy enhances the immune system's ability to ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a ...

A study has demonstrated the potential of a novel ligand-based CAR T-cell therapy for targeting CD7-positive T-cell malignancies, including T-cell acute lymphoblastic leukemia (T-ALL) and T-cell ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

1 These advancements require the expression of T cell-related proteins, such as T-cell receptors (TCRs) and peptide-MHC (pMHC) complexes. However, producing functional TCRs and pMHC complexes in ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...

When it comes to relapsed/refractory follicular lymphoma, chimeric antigen receptor (CAR) T-cell therapy has become a go-to treatment for some patients, with its high end durable response rates ...