are certainly of interest but do not yet provide an informative tool useful in the screening of inhibitors ... steps (ubiquitin tagging, unfolding, and proteolysis) of the ubiquitin/proteasome ...

A new review published in Genes & Diseases explores the pivotal role of the ubiquitin-proteasome system (UPS ... finding for ...

We are mainly interested in two SCF type of ubiquitin ligases (SCFSkp2 and SCFFbx4; Zeng et al. 2010). More recently we developed high throughput screening assays for identifying small molecule ...

ARMC5, a cytoplasmic protein encoded by a gene rich in armadillo (ARM) repeat sequences, has emerged as a critical regulator ...

If you are a molecular or cell biologist, chances are that at some stage you will encounter some aspect of the ubiquitin ... proteasome system affects practically every cellular process. Its ...