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Ubiquitination, an essential post-translational modification, controls various cellular functions by attaching ubiquitin to ...
DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition
Molecular glues are monovalent small molecules that enhance or create protein-protein interaction, leading to the ubiquitination and degradation of target proteins when an E3 ubiquitin ligase ...
© 2025 American Chemical Society and Division of Chemical Education, Inc. Article Views are the COUNTER-compliant sum of full text article downloads since November ...
While inflammasome activation is a well-characterized pathway, the non-inflammasome functions of these ... The CARD domain of ASC can then interact with the CARD domain of pro-caspase-1 to facilitate ...
Department of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas 77843, United States ...
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