VEGF is likely to continue to be considered a central factor in the regulation of angiogenesis, but by no means limited to cancer 104,105. It is also possible that VEGF inhibition will have an ...

Two, that it recruited the vessels by sending out some factor, which we called TAF, tumor angiogenesis factor, because we didn't know what it was that was diffusible. (Diffusion means like if you ...

Lu says the new study demonstrates that, instead of inhibiting dysfunctional tumor angiogenesis by anti-VEGF ... looked at vascular endothelial growth factor (VEGF), a signaling protein that ...

or perhaps by the time the tumor has broken through the basement membrane (as pictured above), angiogenesis takes place. Angiogenesis is the recruitment of blood vessels from the network of ...

Metastatic cancer, the primary cause of cancer mortality, frequently exhibits heightened dependence on certain transcription factors (TFs), which serve as master regulators of oncogenic signaling yet ...

Dr. Erwin Van Meir is a professor in the UAB Department of Neurosurgery. His research interest lies in understanding the molecular basis for human tumor development and how to use this knowledge to ...