Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental ...

A team of researchers from Moffitt Cancer Center has found new insight into why some lung cancer patients do not benefit from ...

Prostate-specific membrane antigen (PSMA) gene expression predicts angiogenesis and response to tyrosine kinase inhibitors (TKIs) in patients with metastatic clear cell renal cell carcinoma (RCC), ...

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer.

Colorectal cancer rates have been steadily increasing in younger adults in recent decades – a phenomenon that has gone largely unexplained. A toxin produced by certain strains of bacteria — in ...

has identified a new key factor contributing to this feature of pancreatic cancer: a previously unknown function of Galectin-1 protein inside the nuclei of fibroblasts. This discovery, published ...

It is a recombinant humanized monoclonal antibody designed to inhibit angiogenesis ... endothelial growth factor (VEGF). This mechanism restricts the blood supply to tumors, thereby slowing ...

Jobevne is a vascular endothelial growth factor (VEGF) inhibitor that binds with VEGF and blocks the interaction with its receptors to prevent angiogenesis, combating cancer by restricting blood ...

describe a new oncogenic function of the STAMBPL1 protein in triple-negative breast cancer (TNBC ... of the transcription factor HIF-1a and its downstream target VEGF, with the consequence of ...

The xenograft tumor tissues were fixed in 3.7% formalin ... This study is the first to uncover the role of STAMBPL1 in promoting angiogenesis through the FOXO1/GRHL3/HIF1α axis. Furthermore, a novel ...