Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published ...

that read the sequence in double-stranded DNA and bind their Hoogsteen complementary target. A Surprise Invasion Inspired by this digital readout of the DNA double helix by groove-binding, triple ...

Please use one of the following formats to cite this article in your essay, paper or report: APA Mandal, Ananya. (2019, June 20). New shape of DNA found in human cells. News-Medical. Retrieved on ...

Family X polymerases such as DNA polymerase ... Figure 4: The triple alanine mutant is deficient in NHEJ of longer gaps. Figure 5: Final conformation of the template strand after molecular ...

"We think this research solves the mystery of how DNA double-strand breaks and the nuclear envelope connect for repair in human cells ... including triple-negative breast cancer, which is ...

pathway 1 (LINP1), which is overexpressed in human triple-negative breast cancer. We found that LINP1 enhances repair of DNA double-strand breaks by serving as a scaffold linking Ku80 and DNA-PKcs ...

We already know DNA can come in other forms, such as triple helices or cruciforms. And the i-motif is not the first four-stranded structure to be found in human cells; scientists already did that ...

On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand ...

Scientists have uncovered a critical role for rapid DNA repair in maintaining genome stability. A new study reveals that ...