Huntington’s disease arises from a genetic mutation that results in an abnormal expansion of the CAG trinucleotide sequence in the huntingtin (HTT) gene. This mutation causes the huntingtin ...

How do mutations happen, and how do they influence the future of a species? Molecules of sickle-cell hemoglobin stick to one another, forming rigid rods. These rods cause a person's red blood ...

A small-molecule ligand that binds to a (CAG) n hairpin repeat is the basis of a biosensor to detect repeat length, which may help diagnose trinucleotide repeat disease severity. DNA trinucleotide ...