The compartmentalization of the thymus is critical for enabling the correct development and selection of developing T cells as specialized processes occur in different morphological layers that ...

Entering the thymus, precursor lymphocytes interact with the thymus stromal compartment mainly built of epithelial cells, and from the enormous variety of produced lymphocytes, only the specific ones ...

“Our discovery—the regulatory T cell recirculation back to the thymus—promotes repair through a process that hasn’t been described before and represents a novel pathway to regeneration ...

The team’s study results, published today in the journal Immunity, outline their discovery of a specific type of regulatory T cell that can home back into the thymus and repair the organ when it ...

NEW YORK, Jan. 16, 2025 /PRNewswire/ -- The Food and Drug Administration (FDA) approved the first mesenchymal stromal cell (MSC) therapy, RYONCIL®, indicated for steroid-refractory acute graft ...

E1 is produced by secretion of androstenedione by the ovarian stroma and the adrenal gland and is aromatized to E1 in the peripheral circulation. Conversion to E1 occurs primarily in adipose ...

The nodules scattered diffusely throughout both lungs are composed of large, bizarre, poorly differentiated, anaplastic cells embedded in a fairly dense fibrous stroma. Figure 4 Section of a ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The authors describe a ...

Between 2001 to 2011, annual age-adjusted incidence increased from 0.55/100,000 to 0.78/100,000, demonstrating an increasing trend with age. Incidence peaks in individuals over 70 years of age ...

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