Organoid models are also limited by the great variability among organoids and the absence of predefined axis. Lancaster and Knoblich have described a protocol for ’generating 3D brain tissue (…) which ...

On-chip vascular bed (VB) system, which enables a three-dimensional tissue to be cultured on a perfusable vasculature, is useful to overcome the current limitation of a kidney organoid (KO): the lack ...

In this work, the supramolecular organization in calf-thymus DNA solution, with low degree of entanglement, appearing under flow was studied in a wide DNA concentration range from 2 to 10 mg/mL, at a ...

Recognition of self-peptide–MHC complexes in the thymus is necessary for thymocyte survival, but can also result in cell death. Here, the authors provide a unique insight into this apparent ...

Liver Organoid Breakthrough: Organ-Specific Vessels Made Cincinnati Children's Hospital Medical Center CINCINNATI – Scientists from Cincinnati Children's and colleagues based in Japan report achieving ...

The current research models of breast cancer are usually limited in their capacity to recapitulate the tumor microenvironment in vitro. The lack of an extracellular matrix (ECM) oversimplifies ...

This valuable study reports the development of a novel organoid system for studying the emergence of autorhythmic gut peristaltic contractions through the interaction between interstitial cells of ...

Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures ...