Scientists have uncovered a crucial pathway that may help preserve thymic function as we age. The findings focus on ...

The University of Texas Health Science Center at San Antonio (UT Health San Antonio) scientists have uncovered a crucial pathway that may help preserve thymic function as we age.

Using a fate-mapping autoimmune arthritis mouse model ... needed for T reg cells to enable immune responses to pathogens without triggering autoimmunity. Data now show that thymus-derived self ...

In mouse model experiments, increasing FGF21 preserved both the size and function of the thymus, allowing for greater T-cell variation. Inside the labyrinth: How thymic structures rebuild Stromal ...

Bispecific T cell engagers (TCEs), which simultaneously target CD3 on the surface of T cells and a tumor-associated antigen (TAA) located on cancer cells, have shown great promise in tumor treatment.

The Jackson Laboratory, Sacramento, CA. Search for other works by this author on: ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Primary cilia are cell signalling and ...

INmune Bio Inc., a clinical-stage biotechnology company targeting inflammation and immunology through the innate immune system, announced a major intellectual property milestone with respect to its ...

This represents an important resource for future studies on mouse germ cells. Male C57Bl/6J mice were purchased from Janvier Laboratories (France) and bred in-house to C57Bl/6J primiparous females to ...

This study presents a useful reassessment of the potential role of dendritic cell-derived IL-27 p28 cytokine in the functional maturation of CD4+CD8- thymocytes, and CD4+ recent thymic emigrants ...

Using advanced microscopes that capture brain cell anatomy and activity, a portion of a mouse's brain was mapped and rendered into a 3D atlas that creates new possibilities for neuroscience.