Department of Pharmaceutics, School of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, ...

In this study, we have performed a glycosphingolipidomics study of mouse thymus, and studied mice mutants which are deficient in β-hexosaminidase b or α-galactosidase A, two glycosidases that are up- ...

However, compared to Hematoxylin and Eosin (H&E) staining, the preparation process of IHC staining is more complex and expensive, which limits its application in clinical practice. Therefore, H&E to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Osteoclasts are bone resorbing cells that are ...

Tumor purity as confounder for the determination of tumor mutational burden (TMB). This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not include a full text ...

Abstract: In histopathology, the tissue slides are usually stained by common H&E stain or special stains (MAS, PAS, and PASM, etc.) to clearly show specific tissue structures. The rapid development of ...

Conditional deletion of Snai1 in the mouse intestine establishes its role in determining ... C, E, G, I. Immunohistochemical staining for Snai1/2 (Abcam ab85931) (C) E14.5 midgut, (E) E14.5 hind gut, ...

Mouse thymus and spleen were isolated and formalin-fixed, followed by embedding in paraffin. Paraffin sections were used for routine H&E staining. CD4 (Abcam, ab183685) levels were detected using ...

Using elegant live imaging approaches, the authors provide convincing evidence in support of an updated model for how positive-selected thymocytes are called into the thymus medulla to interact with ...

For characterizing tissue, the use of H&E is by far preferred for viewing cellular and tissue structure detail. The variation of stain intensity is often driven by the slide reviewers' learning ...

such as tissue embedding and cryosectioning followed by standard histology or immunofluorescent staining without loss of fluorescence signal from endogenous or synthetic reporters. Furthermore, we ...