Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive form of blood cancer that can occur in both children and ...

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional ...

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

Immunologists at UNIGE have revealed a previously unknown anti-tumor role of CD4 T lymphocytes, marking a breakthrough that ...

Results Patients with IMDs were stratified into two clusters based on their immunophenotypes. Cluster 1 was enriched with differentiated B cells, including unswitched memory B cells (USM B), switched ...

Isolated B cells and Tfh cells were cocultured as previously described with minor modifications (23, 24). 3×10^5/well B cells were cultured with or without 1.5×10^5/well Tfh cells in the presence of ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid ...

Systemic lupus erythematosus (SLE) is characterised by numerous abnormalities in B lineage cells, including increased CD27++ plasmablasts/plasma cells, atypical CD27-IgD- B cells with increased CD95, ...

Immune cell feedback drives thymus's complex architecture, new model reveals by Ludwig Maximilian University of Munich edited by Lisa Lock, reviewed by Robert Egan Editors' notes ...

The B-1 cell population derives from splanchno-pleural area and fetal liver and differentiates into CD5 + CD19 + CD23 – CD43 + IgM high IgD low B-1a and CD5 – CD19 + CD23 – CD43 + IgM high IgD low ...