If the infecting phage is virulent, the infection follows a lytic cycle, or for temperate phages, a lysogenic cycle occurs. Scientists have developed non-personalized and personalized phage therapy ...

The observed rapid cleavage of ICP4 indicates that a T-cell response to virus-infected cells can quickly remove a protein that is important for the initiation of the lytic replication cycle.

Depending on the life cycle of the phage, this lysis can occur either soon after the initiation of infection (lytic cycle) or instead following lengthy periods of delay (lysogenic cycle).