In male germ cells, KDM2A specifically demethylates H3K36me3, thus increasing H3K36me2 levels. KDM2A interacts with E2F1 and HCFC1 to facilitate meiotic gene expression and ensure proper meiotic ...

In conclusion, according to data obtained in clinical and experimental studies, the presence of serotonin receptors in the vas deferens, epididymis, testis, Sertoli and Leydig cells, and sperm cells ...

PRAP1, BST2, and CCDC62 were co-expressed with SOX9 (classical marker of Sertoli cell) in testes tissues also confirmed by immunofluorescence. The interaction between germ cell subtypes and Sertoli ...

In this study, Wang and colleagues generate single-cell transcriptome and chromatin accessibility data from testicular tissues of two OA and ... Then they propose a role of specific Sertoli cell ...

AAV gene therapy and cytokine immunotherapy, into a single modality which we believe will redefine how we destroy tumor cells and elicit anti-tumor immunity. Our vision is for Universal AAV ...

Feasibility of an adapted schedule of carboplatin plus paclitaxel in elderly women with advanced ovarian cancer: A retrospective cohort. Patients receiving chemo based on stage and differentiation.

Results: Our analyses confirmed the presence of Pxr transcripts in the mouse testis, particularly in Leydig cells. In addition, A lower testosterone concentration was measured in MLTC-1PxrKD cells ...

We have more information about testicular cancer treatment. Sometimes, the cancer found in the testicle is not a germ cell tumour, but another type of cancer. These include rare types of cancer called ...