Carbohydrate-Based Drug Research Center, State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China Department of Analytical ...

State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, Hunan University, Changsha 410082, P ...

Many proteins group together in what are called protein complexes to carry out biological functions. The traditional method of generating antibodies by immunizing animals struggles to make ...

“As a physician who treats patients with Parkinson’s disease, the recent elucidation of the human PINK1 protein structure bound to mitochondria is a significant and encouraging development ...

solving a decades-long mystery by determining the first structure of the human protein PINK1 bound to mitochondria. First discovered more than 20 years ago, PINK1 is a protein directly ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

PySSA ('Python rich client for visual protein Sequence to Structure Analysis') is an open software project that aims to combine PyMOL(TM) and ColabFold to enable the prediction and analysis of 3D ...

Tertiary lymphoid structure (TLS) formation favors tumour- infiltrating-lymphocyte (TIL) recruitment and is regarded as an important indicator of good prognosis associated with immunotherapy in ...

Amino acids are the building blocks that form polypeptides and ultimately proteins. Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein ...

Background: A tertiary lymphoid structure (TLS) is a crucial component of the tumor microenvironment, which reflects the anti-tumor immune response in the host. The aim of the present study was to ...