Two views of an expanded skin cell nucleus from a person with progeria: On the left, antibody fluorescence imaging shows the ...

In summary, iceLogo provides a robust, probability-based analysis and improved visualization of consensus sequences in multiple aligned peptide sequences by allowing the user to define a custom ...

However, a more complex dodecahedral link emerged after they introduced further modifications to the peptide sequence during attempts to functionalize M 24 L 24, a smaller cubic link. Beyond its ...

A proteomics-driven 24-protein classifier improves the differentiation of thyroid adenoma and carcinoma, retrospectively and ...

Researchers developed a large dodecahedral structure through the self-assembly of metal ions and peptides, with potential implications in drug delivery systems and molecular transportation. (Image: Dr ...

Our method begins with peptide sequence generation via a recurrent neural network (RNN) trained on the acp740 dataset. The generated sequences undergo rigorous filtration: Tier-1 employs three deep ...

The final dataset consisted of 328,832 unique tryptic peptide sequences. This dataset was randomly split into subsets for training and testing (90:10). From the training set, 20% was randomly sampled ...

The CCS of a peptide is a reproducible physicochemical property influenced by its mass, charge, and gas-phase structure. Despite its importance, predicting CCS using both sequence data and physical ...

Department of Biomedical Sciences, Heritage College of Osteopathic Medicine (HCOM), Ohio University, Athens, Ohio 45701, United States Ohio Musculoskeletal and Neurological Institute (OMNI), Heritage ...

However, the structural basis of the interactions remains unclear. This study employs molecular dynamics (MD) simulations to investigate the complete binding process of GB peptides (GB3.1 and GB3.2) ...