In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to ...

This study reveals the step-wise establishment of nuclear speckle-associated domains (SPADs) during mouse embryogenesis.

The TAD-ST3TX-K and TAD-ST3TX-SW speaker stands are designed to enhance the performance of the ME1TX, featuring a slanted design for superior sound reflection management and high-quality sound ...

Researchers at Université Paris-Saclay studied the 3D genome architecture of the tomato, focusing on histone modifications and RNA polymerase II distribution The study found that the abnormal ...

Chromatin organization plays a key role in gene regulation throughout the cell cycle. Understanding the dynamics governing the accessibility of chromatin is crucial for insight into mechanisms of gene ...

Topologically associating domains (TADs) are local chromatin interaction domains, which have been shown to play an important role in gene expression regulation. TADs were originally discovered in the ...

Genes overlapping such weakened TAD boundaries showed transcriptional dysregulation. This study identifies Prmt5 as a broad regulator of gene expression, including regulation of early adipogenic ...

CTCF, together with cohesin, mediates long-range chromatin loops and defines TAD borders (Wutz et al., 2017). Temperature stress induces changes in CTCF occupancy and, associated with these changes, ...