These processes are regulated by the cytokines TGF ... connective tissue growth factor (CTGF) in serum might provide information on fibrogenic activity. The extension of pathogenetic concepts of ...

More information: Frederik Link et al, ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation, Gut (2024). DOI: 10.1136/gutjnl-2024-333213 ...

Programs address the need for disease-modifying therapies targeting root causes of fibrosis Funding will support ... other CCN family members, including CTGF/CCN2 and WISP1/CCN4, on multiple ...