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Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...
In a lab in the heart of Boston, professor Bree Aldridge leads a team of researchers trying to understand a threat that is ...
Researchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric Antigen Receptor T-cell) treatments.
Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.
NOVEL lymph-node-inspired hydrogels enhance CAR T cell activation and proliferation by 50%, offering a more efficient and ...
This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...
Cell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.
Cells are sensitive to many forms of stimuli including light and heat, but little is known about the cellular response to acoustic pressure—a.k.a. sound. A new study suggests that cells can indeed ...
Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...
One concern with in vivo CAR-Ts is the potential insertional mutagenesis of the lentiviral DNA payload, causing secondary ...
In this episode of Teach Me in 10, we’re joined by Thomas Quinn, Takara Bio USA R&D Group Leader, who introduces a ...
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CAR-M technology: A novel approach to overcome CAR-T limitations in solid tumor treatmentCAR-T cell therapy involves extracting a patient's T cells ... allowing safer and more efficient gene transfer. Optimizing transduction timing: The study revealed that macrophages' gene uptake ...
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