Immunotherapies are undoubtedly transforming the landscape of cancer treatment worldwide. By harnessing the body's immune ...

Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity ...

Cell and gene therapies harbor great hopes for biomedicine. They are becoming increasingly important for diseases that are ...

This research roundup discusses researchers’ attempts to find a treatment for a “brain fog” that comes with CAR T-Cell ...

TCG Labs Soleil’s Juri Biosciences is offering EpimAb Biotherapeutics up to $210 million biobucks for exclusive licensing ...

Limiting dietary L-Leu intake is a promising strategy to avoid SLC7A5-mediated allogenic T cell expansion and aGVHD while ...

A next-generation "armored" CAR T cell therapy showed promising results in a small study of patients whose B-cell lymphomas continued to resist multiple rounds of other cancer treatments ...

Antigen-presenting cells rally T cells to the scene, launching an attack on the foreign tissue. These are the first steps of organ transplant rejection. Current immunosuppressants act like ...

A Phase I clinical trial, whose results have been published in the prestigious journal Blood, reveals that this new CAR-T30 therapy promotes the expansion of memory T cells, leading to long ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by ...