In this study, polydimethylsiloxane (PDMS)-based anisotropic topographies (wrinkles) with various topography dimensions were prepared and subsequently combined with native ECMs produced by human ...

FBLG READ THE FULL FBLG RESEARCH REPORT Business Update Preclinical Psoriasis Data Presented at SID Annual Meeting On May 16, 2025, FibroBiologics, Inc. (NASDAQ:FBLG) announced a poster presentation ...

Dilated cardiomyopathy (DCM), characterized by a loss of cardiomyocytes and accumulation of extracellular matrix, is an important cause of congestive heart failure (1 – 3). Most investigations of ...

Concurrently, fibroblasts within the tumor increased ERBB ligand communication with cancer cells, as they differentiated to a proliferative and mesenchymal phenotype in response to TGF β signals from ...

They found that the precursor Vegfc (pro-Vegfc) secreted by slc6a11b+ RAs requires the cooperation of ccbe1+ fibroblasts to be converted into its mature form (mVegfc). This cross-tissue ...

2022). Dermal fibroblasts have traditionally been obtained by skin punch biopsy, which, although a well-established technique, remains an invasive procedure. In addition, successful reprogramming ...

Department of Pharmaceutical Sciences, University of Illinois Chicago, Chicago, Illinois 60612-7231, United States Department of Biomedical Engineering, University of Illinois Chicago, Chicago, ...

Cancer-associated fibroblasts (CAF) influence tumor development at primary as well as in metastatic sites, but there have been no direct comparisons of the transcriptional profiles of stromal cells ...

Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new study by Pascual et al (2025) provides a comprehensive single-cell atlas of ...

Background: Gingival fibroblasts (GFs), as a critical component of periodontal tissue, play a vital role in processes such as collagen synthesis, wound healing, and tissue repair, thereby maintaining ...