Schematic representation of HIV-1 genome organization. The three coding reading frames are depicted along with their open reading frames (rectangles). Genome position is numbered according to HXB2 ...

Paul Sharp and colleagues from the University of Nottingham Queens Medical Centre in England compared full-length genome sequences of chimpanzee HIV strains with inferred ancestral sequences for three ...

HIV-1, like other viruses ... Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus ...

INSTIs block integrase, an enzyme that HIV uses to put HIV DNA into human DNA inside the CD4 T cells. INSTIs belong to a category of drugs known as integrase inhibitors. INSTIs are well ...

At this point HIV has become AIDS ... Scientists worked out the structure of DNA in the 1950s. In 1951 Maurice Wilkins and Rosalind Franklin, both working at King's College, London, were using ...

Early reports have demonstrated that CRISPR effectively excises integrated human immunodeficiency virus type 1 (HIV) from cells. 1,2 For Michele Lai from the University of Pisa, these studies raised ...