Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Mar. 10, 2025 — A new study suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors ...

IgG4-related disease is an increasingly recognized fibroinflammatory condition with protean manifestations. The disorder is ...

Researchers at the University of Pittsburgh have found special high-risk cells in the fallopian tubes that may trigger ...

Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to stress and evade treatment. These circular DNA fragments carry extra copies of ...

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer: a subset of ...

Centre for 3D models of Health and Disease, Division of Surgery and Interventional Science, University College London, London W1W 7TY, U.K. Centre for 3D models of Health and Disease, Division of ...

Knockdown of SMAD3 in pancreatic cancer cells abolished the inhibitory effects of TGF-β on pSTAT3. We further found that tumour-intrinsic STAT3 regulates the durability of the antiproliferative ...

No infant in this study had an abnormal sweat chloride examination, and no histologic abnormalities of the pancreas or exocrine glands were seen. Episodes of suspected aspiration occurred with ...

Stroma is tissue that surrounds the cancer tumor. And that usually includes chemotherapy. "So chemotherapies have a hard time getting in, radiation has a hard time penetrating. Think of pancreatic ...