On May 12, 2025, the U.S. Court of Appeals for the Federal Circuit issued a long-awaited decision in Regents of the University of California v.

The CRISPR-Cas9 patent landscape remains complex and unsettled. The Federal Circuit’s latest decision in University of California v.

After 3 doses of tailor-made treatment, an infant with a rare, life-threatening urea cycle disorder is thriving ...

A Delaware County infant with a rare metabolic disease, CPS1 deficiency, was treated at CHOP with a custom CRISPR therapy.

Why CRISPR-Cas SDN-1 is relevant to the UPSC exam? What is the significance of topics such as Sixteenth Finance Commission, ...

In the most common uses of CRISPR, Cas-9 acts like molecular scissors ... the team incorporated a genetic modification step. This involved inserting genes encoding Cas9 and the guide RNA into ...

“After insertion of the SEED cassette and screening, the screening marker is seamlessly removed by a subsequent CRISPR-triggered repair event, resolved by SSA. In this step, the repeats anneal and the ...

elegans and CRISPR/Cas 9-mediated genome editing ... the other Argonaute proteins, such as AGO2, step in and pick up the slack. Everything continues to operate normally," said Duan.

M.D., Ph.D., at Stanford University—described how it discovered that the order of steps performed in CRISPR-Cas9 gene editing changes how well T cells are protected from a phenomenon known as ...

In contrast, the STEP delivery platform uses molecules that are only 12 ... Through a combination of the new delivery platform and existing CRISPR-Cas-9 gene editing technology, those diseases could ...

Therefore the action of CRISPR-Cas system is usually divided into three steps. An initial step is the acquisition phase where alien DNA is integrated in into the bacterial genome, i.e. the ...