In vitro generation of DCs from mouse and human tissues such as bone marrow and peripheral blood monocytes, has been widely used to study their immunological functions. In chicken, DCs have mainly ...

Sorted classical and non-classical monocytes were cultured in the presence of 100 ng/mL M-CSF for 3 days or an additional 24 hours with RANKL (DC-STAMP ... therapies interfere with monocyte-derived ...

A recent study using a large cohort of organ transplantation donors as source of lymphoid organs, including the spleen, has shown the most complete characterization of human spleen immune cells ...

Chemokines are a family of chemotactic cytokines that play indispensable roles in vascular ... We further validated that the monocyte-derived CXCL12a was essential for guiding this process via the ...

We identify the fat body-derived cytokine, Upd2, in targeting and inducing JAK/STAT signaling in tracheal progenitors to maintain their directional migration. Perturbation of either Upd2 production in ...

49 Extramedullary hematopoiesis has been observed in tissues such as the liver, spleen, and adipose tissue. In these cases, pathogenic stimuli lead to the recruitment of HSC/HSPCs from the bone marrow ...

The recruitment of macrophages in the synovium was examined by immunostaining and monocyte trafficking assay. RNA-seq analysis, Western blotting and chemotaxis experiment were performed on control and ...

Commensal bacteria, TNF and interferon-γ inhibited human DC miR-10a expression in vitro. Anti-TNF mAb treatment significantly promoted miR-10a expression, whereas it markedly inhibited NOD2 and ...

The constant exposure to the content of the lumen and the low-grade inflammation generated by exposure to commensal microbes, promotes a rapid turnover of lamina propria macrophages, which require ...