Researchers found that TEX38 and ZDHHC19 co-localize on the plasma membrane of spermatids and mediate S-palmitoylation of ARRDC5, a crucial protein for spermatogenesis. Disrupting either TEX38 or ...

The linker histone H1 binds to the nucleosome core particle at the site where DNA enters and exits, and facilitates folding of the nucleosomes into a higher-order chromatin structure in eukaryotes.

"While some genes that are essential for spermiogenesis have been identified, there is much that remains unknown about the molecular mechanisms of this intricate process." To explore factors that may ...

In contrast, XAP5L negatively regulates the expression of ciliary genes via repressing these ciliary transcription factors during the spermiogenesis stage. Our results provide new insights into the ...

This study is not a mere enumeration of the phenotypes, but a strong substantiation of DNAH12's essentiality in spermiogenesis, especially in axonemal assembly. The analyses conducted include basic ...

The essential role that m 6 A plays in the regulation of spermatogonia mitosis, meiosis and spermiogenesis in mammals has been recently reviewed (Gui and Yuan, 2021) and is schematically summarized.