The peptides were produced using standard solid phase peptide synthesis with Fmoc chemistry ... using a dialysis membrane tube (Spectra Por Biotech cellulose ester tube, 1 MDa MWCO, Spectrum ...

In a bid to break into the CDMO business at one of its most lucrative angles, India's Granules is snapping up Swiss contract manufacturer Senn Chemicals. The deal, once closed, will immediately ...

BioDuro’s new facility features a kilogram-scale peptide laboratory with automated solid-phase peptide synthesizers, cleavage systems and freeze-drying equipment, supporting peptide synthesis ...

This is the latest facility launch for BioDuro, following a kilogram laboratory and compound management center, both on the same site, in October 2024. The contract research, development, and ...

Solid phase manufacturing can create new custom metal alloys through an innovative process called solid phase alloying, researchers report. Metal scrap can be directly transformed and upgraded ...

"Our new LPPS technology provides a significantly more cost-efficient and environmentally sustainable solution when compared to traditional solid-phase peptide synthesis, substantially reducing ...

Peptides can be synthesized in a handful of ways, but the most common industrial method is solid-phase peptide synthesis (SPPS), according to Rodney Lax, a former business development manager at ...

Two immune checkpoint inhibitors are being evaluated together in a phase 1 trial for certain patients with advanced solid tumors. A combination of a novel checkpoint inhibitor IGSF8 plus Keytruda ...

“hands-free” solid-phase extraction. Protein denaturation, reduction, and alkylation are performed to provide the proteolytic enzyme access to digestion sites for a more complete digestion (3). The ...

The site will add two fully equipped lines comprised of a solid phase peptide synthesizer, high-pressure liquid chromatography, liquid phase isolation equipment, and quality control laboratories. The ...

Introduction: Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant ... a total of 6 washes. Using solid-phase ...