This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

A recent video produced by Vapourtec highlights the patented automatic Variable Bed Flow Reactor (VBFR) demonstrating fully ...

IDE849 is in an ongoing multi-site open label Phase 1 clinical trial for advanced solid tumors (NCT06443489) by Jiangsu Hengrui Pharmaceuticals Co., Ltd. (Hengrui Pharma, SHA: 600276). In this ...

The scalability and reproducibility of ECO Synthesis manufacturing processes A groundbreaking machine learning tool to optimize ligase selection and fragment design An emerging capability to control ...

Tagworks initiated first-in-human phase 1 clinical development of TGW101 in a multicenter, open-label, dose-escalation trial in patients with advanced solid tumours. The primary objectives of the ...

Interleukin-13 receptor α-2 (IL13Rα2) is a cell surface receptor frequently expressed in solid malignancies ... effective dosimetry of 177 Lu-labeled KLG-3 therapy. Targeting with KLG-3 was ...

Microscopic imaging analysis on Alexa Fluor 647-labeled ASO and Chol-HDO. C57BL/6 mice were injected intravenously with Alexa Fluor 647-labeled ASO and Chol-HDO. At 4 h after injection, the brain ...

As people are exposed to more information from more sources than ever before, how they define and feel about “news” has become less clear-cut. Most people agree that information must be factual, up to ...