This important study investigated whether the nuclear receptor Nur77 is regulated by a non-canonical mechanism of ligand-induced disruption of its interaction with RXRg, similar to the family member ...

The story of chronic itch and its impact on quality of life is one dermatologists have heard often. Until recently, treatment ...

Phase 3 trial results released by Protagonist Therapeutics has revealed that icotrokinra, an oral IL-23 receptor inhibitor, achieved clear or nearly clear skin in 66% of patients with ...

Johnson & Johnson (J&J) has reported new data from the Phase III ICONIC-TOTAL trial, assessing icotrokinra in treating plaque ...

Schematic model of the excretion of bitter substances by the ... But this latest study shows that among skin cells, at least, the receptors might have some benefit in surviving exposure to toxins.

Get Instant Summarized Text (Gist) A machine learning method, Mal-ID, effectively diagnoses multiple diseases using B cell and T cell receptor sequences. It accurately distinguishes between ...

Illustration of bitter taste receptor function in keratinocytes. On the left, harmful substances enter skin cells, leading to cellular damage. On the right, bitter taste receptors located in the ...

British model Danielle Lloyd recently shared a deeply personal and emotional message with her fans on Instagram, revealing that she has been diagnosed with skin cancer. The 41-year-old ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

Image Credit: kei907/Shutterstock.com Human skin receptors, particularly mechanoreceptors ... scores for all skin treatments in all skin model geometries. This demonstrated the correlation ...