One of the longstanding challenges in chemical biology has been finding ways to directly observe biological processes at work ...

The HGNC endeavours to approve symbols for all classes of genes that are supported by gene annotation projects and began working on non‐coding RNA (ncRNA ... as well as a guide to how we name them.

Abstract: Recently, the fast development of single-cell RNA-seq (scRNA-seq) techniques has enabled high-resolution transcriptomic statistical analysis of individual cells in heterogeneous tissues, ...

We verified their reliability in single-cell RNA sequencing (scRNA-seq ... and the cells were transfected with miR-4739 inhibitor and inhibitor NC. The transfection reagent and RNA were diluted in ...

Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel 4070, Switzerland ...

While continuous optimization of the prime editing enzymes and guide RNAs ... 24 h post-transfection, with medium replacement every 3 days. The antibiotic selection was maintained for 3 weeks. Next, ...